Cinpathogen areas of scientific expertise:
- Hematology/Hematopathology
- Toxicology
- Oncology
- Immunology
- Molecular Pathology and Epidemiology
- Hematopoietic and lymphoid diseases
- Neoplasia
- Inflammatory/immune mediated mechanisms of disease
- Integrated preclinical/clinical trial paradigms
Research areas:
- Progressive bone marrow failure /neoplasia (AA, MDS, AML, CLL, PB/PT-ALL).
- Development of predictive in vitro tests to evaluate potential for development of AA/MDS.
- Screening tests to identify biomarkers and provide early diagnosis, improve sensitivity and specificity of dx classification
- Identification of therapeutically and mechanistically relevant disease classifications
- Correlation of molecular/diagnostic patterns with clinical outcomes
- Identification of polymorphisms of susceptibility
- Analysis of disease prevalence/incidence
- Immunologically based mechanisms of carcinogenesis and clonal selection
- Epigenomics/altered gene expression/target identification
- Identification of biomarkers of susceptibility and outcome
